Description

15-Fluoro-13,14-Dehydrocarbacyclin is a chemically modified, fluorinated analog of the natural prostaglandin carbacyclin. This compound is significant for its enhanced metabolic stability and targeted biological activity, making it a valuable synthetic intermediate and research tool. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel therapeutic agents and advanced prostaglandin-based research.

Application

• Pharmaceutical Research & Development: As a key synthetic intermediate in the development of novel prostaglandin receptor agonists and antagonists for cardiovascular and pulmonary therapies.
• Biochemical Research: Used as a stable, fluorinated probe to study prostaglandin signaling pathways, receptor binding, and metabolic processes in vitro.
• Fine Chemical Synthesis: Serves as a high-value building block for the custom synthesis of complex, biologically active molecules for preclinical studies.
• Reference Standard: Employed as an analytical standard in HPLC and LC-MS methods for quality control and metabolic studies of related prostaglandin compounds.

Basic Information

Product Name	15-Fluoro-13,14-Dehydrocarbacyclin
CAS No.	120593-19-3
Molecular Formula	C21H31FO3
Molecular Weight	350.47 g/mol
Synonyms	15-Fluoro-13,14-didehydrocarbacyclin; 15-Fluoro-13,14-dehydrocarbacyclin; 15-Fluoro-13,14-didehydro-PGI2 analog; 15-Fluoro-dehydrocarbacyclin; 9-Deoxy-9α,11α-epoxy-15-fluoroprosta-5,13-dien-1-oic acid; 15-F-Carbacyclin analog; Fluorocarbacyclin derivative
EINECS	Contact for details

Quality Control

Our 15-Fluoro-13,14-Dehydrocarbacyclin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC purity analysis, identity confirmation (IR, NMR), and residual solvent testing to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area, away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.