Description

Aflatoxin G1 9,10-Epoxide is a highly reactive and critical metabolite formed from the mycotoxin Aflatoxin G1, representing a key intermediate in understanding its toxicological pathway. This compound is essential for advanced research into the carcinogenic and mutagenic mechanisms of aflatoxins, providing vital insights for toxicology and food safety studies. It is primarily required by analytical laboratories, research institutions, and pharmaceutical companies engaged in metabolite identification, biomarker research, and the development of detection or detoxification strategies.

Application

• Toxicological Research: Used as a standard or reference material in studies investigating the metabolic activation, DNA adduct formation, and carcinogenicity of Aflatoxin G1.
• Analytical Method Development: Serves as a critical calibrant for developing and validating sensitive analytical methods (e.g., LC-MS/MS) for detecting aflatoxin metabolites in biological and environmental samples.
• Biomarker Studies: Employed in research aimed at identifying and quantifying specific DNA or protein adducts as biomarkers of aflatoxin exposure and metabolic processing.
• Food and Feed Safety: Supports research programs focused on understanding the complete risk profile of aflatoxin contamination, aiding in the establishment of safer exposure limits.
• Pharmaceutical Research: Utilized in studies exploring chemopreventive agents or compounds designed to inhibit the formation or activity of this toxic epoxide metabolite.
• Reference Standard Production: Acts as a high-purity chemical for the preparation of certified reference materials (CRMs) used in quality control and regulatory testing laboratories.

Basic Information

Product Name	Aflatoxin G1 9,10-Epoxide
CAS No.	120476-24-6
Molecular Formula	C17H12O8
Molecular Weight	344.27 g/mol
Synonyms	8,9-Epoxy-7-hydroxy-4-methoxy-2,3,6a,8a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione; Aflatoxin G1-8,9-epoxide; AFG1-8,9-exo-epoxide; 2,3,6a,8a-Tetrahydro-8,9-epoxy-7-hydroxy-4-methoxycyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione
EINECS	Contact for details

Quality Control

Our Aflatoxin G1 9,10-Epoxide is produced and handled under strict quality-controlled conditions to ensure identity, purity, and stability for research applications. Each batch is characterized using advanced analytical techniques, including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identification, and impurity profiles is provided to guarantee material integrity and support reproducible scientific results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms
Purity (HPLC)	≥ 95%
Related Substances (HPLC)	≤ 5.0% total
Solubility	Soluble in DMSO, Acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.