Description

Mn(III) Protoporphyrin IX Chloride is a synthetic metalloporphyrin complex where manganese is coordinated in the +3 oxidation state within the protoporphyrin IX macrocycle. This compound is valued for its role as a stable, functional heme analog, serving as a critical biochemical tool and catalyst precursor. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biochemical research, and fine chemical synthesis sectors for applications ranging from enzyme inhibition studies to the development of novel catalytic systems.

Application

• Biochemical Research: Used as a stable heme analog to study heme oxygenase (HO) enzyme inhibition and related metabolic pathways.
• Pharmaceutical Development: Investigated as a potential therapeutic agent for conditions like hyperbilirubinemia due to its inhibitory effects on heme degradation.
• Catalysis: Serves as a precursor or model compound for developing manganese-based oxidation catalysts, mimicking the activity of cytochrome P450 enzymes.
• Analytical Standards: Employed as a high-purity reference standard in chromatographic analysis (HPLC, LC-MS) for porphyrin and metalloporphyrin quantification.
• Material Science: Explored for incorporation into advanced materials, such as sensors or photoactive complexes, due to its distinct optical and redox properties.

Basic Information

Product Name	Mn(III) Protoporphyrin IX Chloride
CAS No.	120389-54-0
Molecular Formula	C34H32ClMnN4O4
Molecular Weight	651.03 g/mol
Synonyms	Manganese(III) Protoporphyrin IX Chloride; MnPP; Manganese Protoporphyrin; Mn(III)-PPIX-Cl; Protoporphyrin IX Manganese(III) Chloride; Heme Oxygenase Inhibitor; 7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(2-)-κN21,κN22,κN23,κN24]manganese Chloride; Manganic Protoporphyrin IX Chloride
EINECS	Contact for details

Quality Control

Our Mn(III) Protoporphyrin IX Chloride is produced under controlled conditions and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Quality is verified through multiple techniques including HPLC, UV-Vis spectroscopy, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider storing desiccated under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Dark brown to purple crystalline powder
Identification (UV-Vis)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.