Description

Isopropyl Unoprostone CAS NO 120373-24-2 is a synthetic prostaglandin analog, specifically a docosanoid derivative, developed for its potent biological activity. This compound is of significant commercial and research interest primarily for its application in ophthalmology. It is essential for pharmaceutical manufacturers and research institutions focused on developing treatments for ocular conditions. The high-purity material is critical for ensuring the efficacy and safety of final drug formulations.

Application

• Active Pharmaceutical Ingredient (API) in ophthalmic solutions for the reduction of intraocular pressure.
• Key Intermediate in the synthesis of novel prostaglandin-based therapeutics.
• Reference Standard for quality control and analytical method development in pharmaceutical laboratories.
• Biochemical Research for studying FP prostanoid receptor activity and related cellular pathways.
• Formulation Development for creating new drug delivery systems, such as sustained-release implants or nanoparticles.

Basic Information

Product Name	Isopropyl Unoprostone
CAS No.	120373-24-2
Molecular Formula	C₂₅H₄₄O₅
Molecular Weight	424.62 g/mol
Synonyms	Unoprostone Isopropyl; UF-021; Isopropyl (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxy-1-buten-1-yl]cyclopentyl]-5-heptenoate; 13,14-Dihydro-15-deoxy-17,18,19,20-tetranorisopropylprostaglandin F2α; Rescula® (brand name active ingredient)
EINECS	Contact for details

Quality Control

Our Isopropyl Unoprostone is manufactured under strict quality management systems to meet the rigorous standards required for pharmaceutical actives. Every batch is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to ensure full traceability and compliance with cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or under refrigeration (2-8°C) as specified. Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container in a dry, well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.