Description

1-Chloro-2,4,5-Tris-Trifluoromethyl-Benzene is a highly fluorinated aromatic building block of significant interest in advanced chemical synthesis. Its value lies in the unique combination of a reactive chlorine substituent and three strongly electron-withdrawing trifluoromethyl groups, which imparts exceptional stability and influences reactivity. This compound is primarily needed by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex molecules, particularly those requiring fluorinated aromatic cores for enhanced metabolic stability, bioavailability, and lipophilicity.
• Agrochemical Active Ingredient Synthesis: Used to construct novel herbicides, fungicides, and insecticides where the trifluoromethyl groups improve weatherfastness and biological activity.
• Liquid Crystal & OLED Material Development: Serves as a building block for fluorinated components in electronic display and lighting technologies, improving performance and durability.
• Specialty Polymer & Resin Modification: Incorporated to enhance chemical resistance, thermal stability, and surface properties of high-performance polymers.
• Catalyst & Ligand Design: Utilized in organometallic chemistry to create sophisticated ligands that modulate catalytic activity in challenging transformations.
• Organic Synthesis Research: A versatile reagent for exploring novel nucleophilic aromatic substitution reactions and cross-coupling methodologies due to its activated chlorine.

Basic Information

Item	Detail
Product Name	1-Chloro-2,4,5-Tris-Trifluoromethyl-Benzene
CAS No.	120326-71-8
Molecular Formula	C9H2ClF9
Molecular Weight	316.55 g/mol
Synonyms	1-Chloro-2,4,5-tris(trifluoromethyl)benzene; Benzene, 1-chloro-2,4,5-tris(trifluoromethyl)-; 2,4,5-Tris(trifluoromethyl)chlorobenzene; α,α,α,α',α',α'-Hexafluoro-2,4,5-tris(trifluoromethyl)chlorobenzene (historical); Chloropentafluoroxylene (related trade context); Perfluorinated chloroxylene analog
EINECS	Contact for details

Quality Control

Our 1-Chloro-2,4,5-Tris-Trifluoromethyl-Benzene is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our commitment to supply chain integrity and regulatory compliance (including REACH) ensures you receive a reliable material for your sensitive applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reactive metals. Due to the presence of fluoride/strong alkali reactive groups, ensure storage areas are free from contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.1%
Chloride Content	Confirmatory test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.