Description

3-(Trifluoromethyl)Imidazo[1,5-A]Pyridine-1-Carboxylic Acid is a high-value, heterocyclic carboxylic acid building block characterized by its fused imidazopyridine core and trifluoromethyl substituent. This compound is essential for medicinal chemistry research and development, offering a versatile scaffold for creating novel bioactive molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of advanced intermediates for drug discovery programs targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its privileged heterocyclic structure.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel herbicides, fungicides, or insecticides, leveraging the biological activity of the imidazopyridine moiety.
• Material Science Precursor: Can be utilized in the development of advanced organic materials, such as ligands for catalysts or components for organic electronics.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes for studying biological pathways and target engagement.

Basic Information

Item	Detail
Product Name	3-(Trifluoromethyl)Imidazo[1,5-A]Pyridine-1-Carboxylic Acid
CAS No.	120221-68-3
Molecular Formula	C9H5F3N2O2
Molecular Weight	230.15 g/mol
Synonyms	1H-Imidazo[1,5-a]pyridine-1-carboxylic acid, 3-(trifluoromethyl)-; 3-(Trifluoromethyl)-1H-imidazo[1,5-a]pyridine-1-carboxylic acid; Imidazo[1,5-a]pyridine-1-carboxylic acid, 3-(trifluoromethyl)-; 120221-68-3; 3-Trifluoromethylimidazo[1,5-a]pyridine-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 3-(Trifluoromethyl)Imidazo[1,5-A]Pyridine-1-Carboxylic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We are committed to supply chain transparency and reliable documentation, with COAs available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.