Description

8-Methylquinoline-5-Sulfonyl Chloride is a specialized organic sulfonyl chloride derivative, serving as a critical building block in advanced chemical synthesis. Its primary value lies in its high reactivity as a sulfonylation reagent, enabling the introduction of the sulfonyl functional group into target molecules with precision. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of novel drug candidates, especially in creating sulfonamide-based active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the sulfonyl moiety is required for biological activity.
• Dye and Pigment Manufacturing: Acts as a precursor in the production of specialized quinoline-based dyes and colorants.
• Material Science Research: Employed in the creation of functionalized polymers and advanced organic materials.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in proteomics and diagnostic assay development.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom chemical synthesis services catering to R&D and scale-up projects.

Basic Information

Product Name	8-Methylquinoline-5-Sulfonyl Chloride
CAS No.	120164-05-8
Molecular Formula	C10H8ClNO2S
Molecular Weight	241.69 g/mol
Synonyms	5-(Chlorosulfonyl)-8-methylquinoline; 8-Methyl-5-quinolinesulfonyl chloride; Quinoline, 8-methyl-, 5-sulfonyl chloride; 8-Methylquinoline-5-sulphonyl chloride; 5-Quinolinesulfonyl chloride, 8-methyl-; 120164-05-8; 8-Methyl-5-sulfonylchloroquinoline
EINECS	Contact for details

Quality Control

Our 8-Methylquinoline-5-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.