Description

3,3,3-Trifluoropropyl Trifluoromethanesulfonate is a specialized fluorinated sulfonate ester, a key reagent in advanced organic synthesis. This compound is highly valued for its role as a potent alkylating and trifluoromethylating agent, enabling the introduction of valuable fluorinated functional groups into target molecules. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for the development of novel active ingredients and performance chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs) containing trifluoropropyl or trifluoromethanesulfonate moieties, enhancing metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the introduction of fluorine atoms improves biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in cross-coupling and fluorination reactions.
• Polymer and Material Science: Employed to synthesize fluorinated monomers and polymers, imparting unique properties such as chemical resistance, low surface energy, and thermal stability to advanced materials.
• Organic Synthesis Reagent: Functions as a versatile reagent for introducing protecting groups or as a substrate in nucleophilic substitution reactions under controlled conditions.
• Fluorine Chemistry Research: A valuable tool in academic and industrial R&D for exploring new methodologies in fluoroorganic chemistry and developing novel fluorinated compounds.

Basic Information

Product Name	3,3,3-Trifluoropropyl Trifluoromethanesulfonate
CAS No.	120097-63-4
Molecular Formula	C4H4F6O3S
Molecular Weight	246.13 g/mol
Synonyms	3,3,3-Trifluoropropyl Triflate; 3,3,3-Trifluoropropan-1-yl Trifluoromethanesulfonate; 1,1,1-Trifluoro-3-(trifluoromethanesulfonyloxy)propane; 3,3,3-Trifluoropropyl Trifluoromethylsulfonate; Trifluoromethanesulfonic Acid 3,3,3-Trifluoropropyl Ester; 3,3,3-Trifluoropropyl Ester of Trifluoromethanesulfonic Acid; 3,3,3-Trifluoropropyl OTf
EINECS	Contact for details

Quality Control

Our 3,3,3-Trifluoropropyl Trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request, supporting compliance with research and cGMP guidelines for advanced intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.