Description

1H-Imidazole-1-Carboxaldehyde, 2,4,5-Trifluoro- (9Ci) is a specialized fluorinated imidazole derivative, a high-value building block prized for its unique reactivity and trifluoromethyl-substituted aromatic core. This compound is essential for introducing the imidazole pharmacophore with enhanced lipophilicity and metabolic stability into target molecules. It is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Development: Used in the creation of advanced herbicides, fungicides, and pesticides where the fluorinated imidazole moiety can improve bioactivity and environmental profile.
• Ligand and Catalyst Synthesis: Serves as a precursor for N-heterocyclic carbene (NHC) ligands and other organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers, organic electronic materials, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized for labeling and modifying biomolecules to study biological processes.

Basic Information

Product Name	1H-Imidazole-1-Carboxaldehyde, 2,4,5-Trifluoro- (9Ci)
CAS No.	120047-74-7
Molecular Formula	C4HF3N2O
Molecular Weight	156.06 g/mol
Synonyms	2,4,5-Trifluoro-1H-imidazole-1-carboxaldehyde; 2,4,5-Trifluoroimidazole-1-carbaldehyde; 1-Formyl-2,4,5-trifluoroimidazole; 2,4,5-Trifluoro-1-imidazolecarboxaldehyde; (2,4,5-Trifluoro-1H-imidazol-1-yl)methanone (tautomer); 1H-Imidazole-1-carboxaldehyde, 2,4,5-trifluoro-; 2,4,5-Trifluoro-1H-imidazole-1-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-1-Carboxaldehyde, 2,4,5-Trifluoro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.