Description

Phosphoramidon is a potent and specific microbial-derived metalloprotease inhibitor, widely recognized for its role in biochemical research and pharmaceutical development. Its primary value lies in its ability to selectively inhibit thermolysin and other zinc metalloproteases, making it a critical tool for studying enzyme mechanisms and signaling pathways. This compound is essential for researchers and manufacturers in the life sciences, biotechnology, and pharmaceutical industries, particularly those focused on protease function, inhibitor screening, and drug discovery programs.

Application

• As a specific inhibitor of thermolysin and related bacterial metalloendopeptidases in enzymatic studies.
• Used in biochemical research to investigate the role of metalloproteases in various physiological and pathological processes.
• Critical reagent in pharmaceutical R&D for screening and developing novel therapeutic protease inhibitors.
• Employed as a standard or reference compound in analytical method development and validation within quality control laboratories.
• Utilized in cell culture and molecular biology applications to modulate specific proteolytic activities.
• Applied in academic research for studying protein degradation, peptide processing, and enzyme kinetics.

Basic Information

Product Name	Phosphoramidon
CAS No.	119942-99-3
Molecular Formula	C₂₃H₃₈N₄O₁₄P
Molecular Weight	634.53 g/mol
Synonyms	N-(α-L-Rhamnopyranosyloxyhydroxyphosphinyl)-L-leucyl-L-tryptophan; Phosphoramidon Disodium Salt; Thermolysin Inhibitor; Streptomyces tanashiensis protease inhibitor; L-N-[(S)-(R)-1-(Rhamnopyranosyloxy)phosphinyl]leucyl-L-tryptophan; NSC 338699; [N-(α-L-Rhamnopyranosyloxyhydroxyphosphinyl)-L-leucyl-L-tryptophan]
EINECS	Contact for details

Quality Control

Our Phosphoramidon is produced and tested under a rigorous quality management system to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles, is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.