Description

U-75302 CAS NO 119477-85-9 is a high-purity, specialized chemical compound widely recognized as a potent and selective antagonist for the leukotriene B4 (LTB4) receptor, BLT1. This compound is crucial for biochemical and pharmacological research, enabling the study of inflammatory pathways and the development of novel therapeutic agents. It is primarily utilized by researchers and development teams in the pharmaceutical, biotechnology, and academic sectors for target validation, assay development, and investigative studies.

Application

• Biochemical Research: As a standard reference compound for studying the role of leukotriene B4 in inflammatory and immune responses.
• Pharmacological Studies: Used in in vitro and in vivo models to investigate BLT1 receptor antagonism and its effects on various disease states.
• Drug Discovery & Development: A key tool for high-throughput screening (HTS) and lead optimization in anti-inflammatory drug discovery programs.
• Academic Research: Employed in university and institutional labs for fundamental research into eicosanoid signaling pathways.
• Diagnostic Development: Potential use in developing assays to measure LTB4 activity or screen for receptor modulators.

Basic Information

Item	Details
Product Name	U-75302
CAS No.	119477-85-9
Molecular Formula	C27H44N2O5
Molecular Weight	476.66 g/mol
Synonyms	U75302; 6-[6-[(3S,4R)-3,4-Dihydroxy-1,5-octadienyl]-2-pyridinyl]-1,5-hexanediol; (E,E,E)-6-[6-(3,4-Dihydroxy-1,5-octadienyl)-2-pyridinyl]-1,5-hexanediol; U-75302 BLT1 antagonist; Leukotriene B4 receptor antagonist U75302; LTB4 antagonist
EINECS	Contact for details

Quality Control

Our U-75302 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.