Description

Glidobactin D is a potent, naturally occurring cyclic depsipeptide antibiotic belonging to the glidobactin family. This compound is of significant interest in biochemical and pharmaceutical research due to its unique mechanism of action as a proteasome inhibitor. It is primarily utilized by research institutions and pharmaceutical companies for investigating novel therapeutic pathways, particularly in oncology and anti-infective drug discovery.

Application

• Biochemical Research: Used as a specific and potent inhibitor of the proteasome complex for studying protein degradation pathways and cellular regulation.
• Anticancer Research: Investigated for its potential to induce apoptosis in various cancer cell lines by inhibiting proteasome activity.
• Anti-infective Development: Serves as a lead compound in the discovery of new antibiotics, particularly against drug-resistant bacterial strains.
• Mechanism of Action Studies: A critical tool for elucidating the role of the proteasome in inflammation, immune response, and other disease states.
• Pharmaceutical Intermediates: Can be used in the synthesis and development of more complex therapeutic agents targeting proteasome inhibition.
• Standards & References: Supplied as a high-purity analytical standard for quality control and method development in laboratory settings.

Basic Information

Product Name	Glidobactin D
CAS No.	119259-73-3
Molecular Formula	C34H57N5O8
Molecular Weight	663.85 g/mol
Synonyms	Glidobactin D; Cinnabaramide A; Syringolin A analog; Proteasome inhibitor Glidobactin D; Cyclic depsipeptide antibiotic; (3S,6S,9S,12S,15S,18S,21S,24S,27S,30S)-3,6,9,12,15,18,21,24,27,30-Decakis(1-methylethyl)-1,4,7,10,13,16,19,22,25,28-decaoxacyclotriacontane-2,5,8,11,14,17,20,23,26,29-decone; (3S,6S,9S,12S,15S,18S,21S,24S,27S,30S)-3,6,9,12,15,18,21,24,27,30-Decaisopropyl-1,4,7,10,13,16,19,22,25,28-decaoxacyclotriacontane-2,5,8,11,14,17,20,23,26,29-decone
EINECS	Contact for details

Quality Control

Our Glidobactin D is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research-grade biochemicals to guarantee reliable and reproducible results in your experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, freezer environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Biological Activity	Proteasome inhibition activity confirmed

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.