Description

D-Amphetamine-D3 Sulfate Salt is a stable isotope-labeled analog of amphetamine, where three hydrogen atoms are replaced by deuterium. This high-purity compound is essential for creating precise and reliable internal standards in quantitative analytical methods. It is primarily utilized by pharmaceutical research laboratories, forensic toxicology departments, and analytical chemistry facilities for method development and validation.

Application

• Internal Standard for Mass Spectrometry (LC-MS/MS, GC-MS): Serves as a critical reference compound for the accurate quantification of amphetamine and its metabolites in complex biological matrices.
• Forensic and Clinical Toxicology: Used in the development and validation of assays for drug testing, workplace screening, and post-mortem analyses.
• Pharmacokinetic and Metabolism Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) in research settings.
• Pharmaceutical Quality Control: Supports impurity profiling and assay development for pharmaceutical formulations containing amphetamine.
• Reference Material for Certified Standards: Acts as a foundational material for manufacturers of certified reference materials (CRMs).
• Research on Neuropharmacology: Employed in specialized research to study the mechanisms of action of psychostimulants without interfering with natural isotopic distributions.

Basic Information

Product Name	D-Amphetamine-D3 Sulfate Salt
CAS No.	119039-59-7
Molecular Formula	C9H10D3N • ½ H2SO4
Molecular Weight	~188.3 g/mol (for free base C9H10D3N)
Synonyms	(+)-Amphetamine-d3 sulfate; Dextroamphetamine-d3 sulfate; (S)-1-Phenyl-2-aminopropane-d3 sulfate; d-Amphetamine-α,β,β-d3 hemisulfate salt; Deuterated Amphetamine Sulfate; Amphetamine-D3; 2S-Amphetamine-d3 sulfate; Internal Standard for Amphetamine
EINECS	Contact for details

Quality Control

Our D-Amphetamine-D3 Sulfate Salt is manufactured under strict quality control protocols to ensure exceptional isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D3), chemical purity, and identity confirmation. We adhere to cGMP principles for traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to expected mass spectrum
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D (D3)
Chemical Purity (NMR)	Conforms to structure
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.