Description

β-Neuraminic Acid, n-Acetyl-2-S-Phenyl-2-Thio-, Methyl Ester, 4,7,8,9-Tetraacetate is a sophisticated, fully protected derivative of neuraminic acid, a crucial sialic acid building block. This compound is specifically engineered for advanced research and synthesis, offering a stable and reactive intermediate for the construction of complex glycoconjugates. It is an essential material for pharmaceutical chemists and biochemists working in glycobiology, antiviral drug discovery, and the development of novel diagnostic reagents.

Application

• Glycoconjugate Synthesis: A key protected intermediate for the chemical and enzymatic synthesis of sialylated oligosaccharides, glycopeptides, and glycolipids.
• Antiviral Research: Used in the development of sialidase (neuraminidase) inhibitors and other antiviral agents targeting pathogens like influenza.
• Biochemical Tool Development: Serves as a precursor for labeled sialic acid analogs (e.g., fluorescent, isotopic) used in metabolic labeling and trafficking studies.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies in drug discovery programs focused on sialic acid-mediated processes.
• Diagnostic Reagent Manufacturing: Used in the production of high-specificity reagents for detecting sialic acid-binding proteins and antibodies.

Basic Information

Product Name	β-Neuraminic Acid, n-Acetyl-2-S-Phenyl-2-Thio-, Methyl Ester, 4,7,8,9-Tetraacetate
CAS No.	118977-25-6
Molecular Formula	C27H33NO12S
Molecular Weight	595.62 g/mol
Synonyms	5-Acetamido-2-S-phenyl-2-thio-3,5-dideoxy-D-glycero-β-D-galacto-non-2-ulopyranosonic Acid Methyl Ester Tetraacetate; Methyl 5-acetamido-2-S-phenyl-2-thio-3,5-dideoxy-D-glycero-β-D-galacto-non-2-ulopyranosonate Tetraacetate; N-Acetyl-2-S-phenyl-2-thio-β-neuraminic Acid Methyl Ester Tetraacetate; Peracetylated S-Phenyl Thiosialoside Methyl Ester; Protected Thiosialic Acid Derivative; S-Phenyl 2-Thio-β-Neu5Ac Methyl Ester Tetraacetate
EINECS	Contact for details

Quality Control

Our β-Neuraminic Acid derivative is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity, suitable for research and development applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive); containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. For long-term storage, desiccants are recommended.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.