Description

Nbqx Disodium Salt is a high-purity, water-soluble salt form of the potent and selective AMPA receptor antagonist, 6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione. This compound is a critical research-grade chemical for investigating glutamatergic neurotransmission pathways. It is primarily utilized by pharmaceutical R&D departments, academic neuroscience laboratories, and biotechnology companies focused on CNS disorders.

Application

• Neuroscience Research: A key pharmacological tool for selectively blocking AMPA-type glutamate receptors in electrophysiology and neuropharmacology studies.
• Drug Discovery & Development: Used in high-throughput screening and target validation for conditions involving excitotoxicity, such as stroke, epilepsy, and neurodegenerative diseases.
• Biochemical Assays: Serves as a reference standard and active control in receptor binding assays and functional cellular tests.
• Academic Studies: Fundamental research into learning, memory, and synaptic plasticity mechanisms in model organisms.
• Preclinical Investigations: Evaluation of neuroprotective strategies in animal models of brain ischemia and trauma.

Basic Information

Product Name	Nbqx Disodium Salt
CAS No.	118876-58-7
Molecular Formula	C14H6N4Na2O7S
Molecular Weight	420.26 g/mol
Synonyms	6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione Disodium Salt; NBQX Disodium; FG 9202 Disodium Salt; AMPA Receptor Antagonist NBQX; 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide Disodium Salt; Disodium 6-Nitro-7-sulfamoyl-2,3-quinoxalinedionate; NBQX-Na2
EINECS	Contact for details

Quality Control

Our Nbqx Disodium Salt CAS NO 118876-58-7 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccant and under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
pH (1% Solution)	7.0 - 9.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.