Description

Humulone, Compd. With 4,5 - Dimethyl - O - Phenylenediamine (6Ci) is a specialized chemical derivative of humulone, a key α-acid found in hops. This compound is significant for its role as a stable, colorimetric derivative used in analytical chemistry for the precise quantification of hop bitter acids. It is primarily required by analytical laboratories, quality control departments in the brewing industry, and research institutions focusing on hop chemistry and beer stability.

Application

• Primary Standard for HPLC Analysis: Used as a high-purity reference standard for the calibration and validation of High-Performance Liquid Chromatography (HPLC) methods in hop and beer analysis.
• Quantification of α-Acids: Essential for the accurate determination of humulone, cohumulone, and adhumulone content in hop cones, pellets, and extracts.
• Brewing Industry QC: Critical for quality control protocols to ensure consistent bittering potential and flavor profile in finished beer products.
• Hop Breeding & Research: Employed in agricultural research to evaluate new hop varieties for their α-acid composition and stability.
• Stability Studies: Used in research to study the degradation pathways of hop bitter acids during storage and brewing processes.
• Method Development: Serves as a key reagent in developing and optimizing new analytical techniques for hop-derived compounds.

Basic Information

Product Name	Humulone, Compd. With 4,5 - Dimethyl - O - Phenylenediamine (6Ci)
CAS No.	118764-42-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Humulone-4,5-dimethyl-o-phenylenediamine adduct; 6Ci derivative of humulone; Humulone DMPD derivative; α-Acid DMPD derivative (6Ci); Hop acid derivative for HPLC; ASBC 6Ci compound; IOB 6Ci standard; EBC 7.4 derivative
EINECS	Contact for details

Quality Control

Our Humulone, Compd. With 4,5 - Dimethyl - O - Phenylenediamine (6Ci) is produced and tested to meet the exacting standards required for analytical reference materials. Each batch is characterized using advanced techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and stability. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your method validation and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere to prevent oxidation and ensure long-term stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to brownish powder or solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (UV/VIS)	Spectrum corresponds to reference standard
Purity (HPLC, Area %)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%
Solubility	Soluble in methanol, acetonitrile
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.