Description

2-(Dimethylamino)Ethane-1-Sulfonyl Chloride Hydrochloride is a versatile and highly reactive sulfonyl chloride derivative, primarily used as a key building block in organic synthesis. Its core value proposition lies in its ability to introduce the sulfonamide functional group, which is critical for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial reagent for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of modern herbicides and fungicides where the sulfonamide moiety enhances efficacy and selectivity.
• Peptide Modification: Employed to selectively sulfonylate amino groups in peptides and proteins for biochemical studies and bioconjugation.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology Probes: Utilized to create activity-based probes for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring the introduction of a dimethylaminoethylsulfonyl group.

Basic Information

Product Name	2-(Dimethylamino)Ethane-1-Sulfonyl Chloride Hydrochloride
CAS No.	118646-39-2
Molecular Formula	C4H11Cl2NO2S
Molecular Weight	216.11 g/mol
Synonyms	2-(Dimethylamino)ethanesulfonyl chloride hydrochloride; N,N-Dimethyl-2-aminoethanesulfonyl chloride hydrochloride; DMAS-Cl hydrochloride; (2-Dimethylaminoethyl)sulfonyl chloride hydrochloride; 2-(Dimethylamino)ethylsulfonyl chloride hydrochloride; N,N-Dimethylethylaminesulfonyl chloride hydrochloride; Amino Sulfonyl Chloride Hydrochloride Derivative
EINECS	Contact for details

Quality Control

Our 2-(Dimethylamino)Ethane-1-Sulfonyl Chloride Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.