Description

o-Mesitoyl n-Benzyloxycarbonylphenylalanyl-Glycine Hydroxamate is a specialized synthetic peptide derivative designed as a potent and selective enzyme inhibitor. This compound matters for researchers and developers in pharmaceutical discovery, as it serves as a critical biochemical tool for studying protease and metalloproteinase activity. It is primarily needed by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in drug development, particularly for programs targeting inflammatory diseases, cancer, and other conditions involving matrix metalloproteinases (MMPs).

Application

• Biochemical Research: Used as a reference standard and active inhibitor in enzymatic assays to study inhibition kinetics and mechanisms.
• Pharmaceutical Development: Serves as a key intermediate or lead compound in the synthesis of novel therapeutic agents targeting specific proteases.
• Proteomics & Drug Discovery: Employed in high-throughput screening (HTS) platforms to identify and validate new drug targets related to protease activity.
• Academic Research: Utilized in university and institutional labs for fundamental research into enzyme structure, function, and signal transduction pathways.
• Inhibitor Synthesis: Acts as a sophisticated building block for the chemical synthesis of more complex, tailored enzyme inhibitors.

Basic Information

Product Name	o-Mesitoyl n-Benzyloxycarbonylphenylalanyl-Glycine Hydroxamate
CAS No.	118292-30-1
Molecular Formula	C27H27N3O6
Molecular Weight	489.52 g/mol
Synonyms	o-Mesitoyl Z-Phe-Gly-NHOH; Z-Phe-Gly Hydroxamic Acid, o-Mesitoyl Derivative; N-[(Benzyloxy)carbonyl]-L-phenylalanylglycine Hydroxamic Acid, 2',4',6'-Trimethylbenzoyl Derivative; (2S)-2-[[(2S)-2-[[(Benzyloxy)carbonyl]amino]-3-phenylpropanoyl]amino]-N-hydroxyacetamide, 2,4,6-Trimethylbenzoyl Derivative; CAS 118292-30-1; MMP Inhibitor Intermediate; Peptidyl Hydroxamate Inhibitor
EINECS	Contact for details

Quality Control

Our o-Mesitoyl n-Benzyloxycarbonylphenylalanyl-Glycine Hydroxamate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.