Description

2-Fluoro-4-Trifluoromethyl-Pyridine is a versatile fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its value lies in the unique electronic properties imparted by the fluorine and trifluoromethyl substituents, which are crucial for modulating the biological activity and physicochemical characteristics of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials requiring specific fluorine content.
• Fluorine Chemistry Building Block: A valuable starting material for further functionalization in medicinal and discovery chemistry programs.

Basic Information

Product Name	2-Fluoro-4-Trifluoromethyl-Pyridine
CAS No.	118078-66-3
Molecular Formula	C6H3F4N
Molecular Weight	165.09 g/mol
Synonyms	4-(Trifluoromethyl)-2-fluoropyridine; 2-Fluoro-4-(trifluoromethyl)pyridine; 2-Fluoro-α,α,α-trifluoro-picoline; Pyridine, 2-fluoro-4-(trifluoromethyl)-; 2-Fluoro-4-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Trifluoromethyl-Pyridine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to ensure high chemical purity and identity. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.