Description

N(Alpha)-(2-Naphthylsulfonylglycyl)-4-Oxamidinophenylalanine Piperidide is a specialized, high-purity synthetic peptide derivative designed for advanced research and development. This compound is valued for its role as a potent and selective inhibitor of specific serine proteases, making it a critical tool in biochemical pathway analysis. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies engaged in drug discovery, particularly for investigating coagulation, inflammation, and oncology-related targets. The product is supplied with comprehensive analytical documentation to ensure reliability and reproducibility in sensitive experimental applications.

Application

• Pharmaceutical Research & Development: Serves as a key biochemical tool and reference standard in the discovery and validation of novel therapeutic agents targeting serine proteases.
• Enzyme Inhibition Studies: Used in vitro to study the kinetics, specificity, and mechanism of action of target enzymes like trypsin, thrombin, and related proteases.
• Biochemical Assay Development: Employed as a critical component in developing high-throughput screening (HTS) assays and diagnostic test kits.
• Academic & Institutional Research: Supports fundamental research in biochemistry, cell biology, and pharmacology to elucidate disease mechanisms.
• Process Development & Optimization: Acts as a model compound or intermediate in the development of synthetic routes for related peptide-based inhibitors.

Basic Information

Product Name	N(Alpha)-(2-Naphthylsulfonylglycyl)-4-Oxamidinophenylalanine Piperidide
CAS No.	117855-58-0
Molecular Formula	C32H35N5O6S
Molecular Weight	617.71 g/mol
Synonyms	NSC 332007; 4-Amidinophenylalanine Piperidide, N-(2-Naphthylsulfonylglycyl)-; N-(2-Naphthalenesulfonylglycyl)-4-amidinophenylalanine piperidide; 2-Naphthalenesulfonyl-Gly-4-Amidino-Phe-Pip; (4-Amidinophenylalanyl)piperidide, N-(2-naphthylsulfonylglycyl)-; FFR-piperidide (2-Naphthylsulfonyl derivative); Trypsin Inhibitor (Peptidic); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of N(Alpha)-(2-Naphthylsulfonylglycyl)-4-Oxamidinophenylalanine Piperidide is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the exacting standards of research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, identity confirmation by spectroscopic methods (NMR, MS), and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The compound is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular ion [M+H]+
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.