Description

17-(4-Azidophenyl)-18,19,20-Trinorprostaglandin E2 is a specialized, high-purity synthetic prostaglandin analog featuring a photoreactive azido group. This compound is critically important for advanced biochemical and pharmaceutical research, serving as a key intermediate or active probe in the development of novel therapeutic agents. It is primarily utilized by research scientists and development teams in the pharmaceutical, biotechnology, and life sciences sectors for targeted drug discovery and molecular biology studies.

Application

• Biochemical Research Probe: Used as a photoaffinity labeling agent to study prostaglandin receptors and enzyme binding sites.
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel prostaglandin-based drug candidates.
• Mechanism of Action Studies: Enables the investigation of cellular signaling pathways mediated by prostaglandin E2 analogs.
• Proteomics and Target Identification: Facilitates the identification and isolation of proteins that interact with prostaglandin pathways.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Academic Research: Supports fundamental research in inflammation, pain, and reproductive biology at universities and research institutes.

Basic Information

Product Name	17-(4-Azidophenyl)-18,19,20-Trinorprostaglandin E2
CAS No.	117625-46-4
Molecular Formula	C26H35N3O5
Molecular Weight	469.57 g/mol
Synonyms	17-(4-Azidophenyl)-18,19,20-trinor-PGE2; PGE2 Azido Derivative; 17-(p-Azidophenyl)-18,19,20-trinorprostaglandin E2; Azido-PGE2; Prostaglandin E2 Azidophenyl Analog; 117625-46-4; 4-Azidophenyl-trinorprostaglandin E2
EINECS	Contact for details

Quality Control

Our 17-(4-Azidophenyl)-18,19,20-Trinorprostaglandin E2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area. Allow the product to reach room temperature in its sealed container before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.