Description

5,12,19-Trihydroxy-6,8,10,14-Eicosatetraenoic Acid is a specialized eicosanoid derivative, a class of bioactive lipid mediators with significant signaling functions. This compound matters for its role as a potential intermediate or reference standard in advanced biochemical research and pharmaceutical development. It is primarily needed by researchers and manufacturers in the life sciences sector, particularly those focused on inflammation pathways, lipidomics, and the synthesis of novel therapeutic agents.

Application

• Biochemical Research: Used as a high-purity reference standard or analytical standard in lipidomics and eicosanoid profiling studies.
• Pharmaceutical R&D: Serves as a key intermediate or building block in the synthesis of novel anti-inflammatory or pro-resolving lipid mediators.
• Cell Signaling Studies: Employed in in vitro assays to investigate specific receptor interactions and downstream metabolic pathways related to inflammation and resolution.
• Academic Research: Utilized in university and institutional laboratories for fundamental research on arachidonic acid metabolism and oxylipin biology.
• Diagnostic Development: Can be used in the development and calibration of diagnostic kits or assays designed to detect specific eicosanoid profiles in biological samples.

Basic Information

Product Name	5,12,19-Trihydroxy-6,8,10,14-Eicosatetraenoic Acid
CAS No.	117605-61-5
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.47 g/mol
Synonyms	5,12,19-TriHETE; (5Z,8Z,10E,12S,14Z)-5,12,19-Trihydroxyicosa-6,8,10,14-tetraenoic acid; 5,12,19-Trihydroxy-6,8,10,14-eicosatetraenoate; 5,12,19-Trihydroxyicosatetraenoic acid; 19-Hydroxy-5,12-diHETE; 5,12,19-Trihydroxy-6,8,10,14-icosatetraenoic acid; 5,12,19-TriHETE (117605-61-5)
EINECS	Contact for details

Quality Control

Our 5,12,19-Trihydroxy-6,8,10,14-Eicosatetraenoic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. All products undergo rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing specific test results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95%
Water Content	≤ 1.0% (KF)
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.