Description

Carazolol Glucuronide is a key metabolite of the β-blocker Carazolol, formed via glucuronidation. This compound is of significant importance in pharmaceutical research and development, particularly for metabolic and pharmacokinetic studies. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical and veterinary medicine sectors for analytical reference standards and method development.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantitative and qualitative analysis of Carazolol and its metabolites in biological matrices.
• Metabolite Identification & Profiling: Essential for studying the metabolic pathways, bioavailability, and excretion profiles of Carazolol in preclinical and clinical research.
• Bioanalytical Method Development: Serves as a critical standard for developing and validating sensitive HPLC, LC-MS, or LC-MS/MS methods for drug monitoring.
• Veterinary Drug Residue Analysis: Applied in food safety testing to detect and quantify Carazolol residues in animal-derived products, ensuring compliance with maximum residue limits (MRLs).
• Doping Control: Used in anti-doping laboratories for the detection of β-blocker misuse in both human and equine sports.
• Toxicology Studies: Employed to investigate the disposition and potential long-term effects of Carazolol exposure.

Basic Information

Item	Details
Product Name	Carazolol Glucuronide
CAS No.	117374-84-2
Molecular Formula	C23H31N3O8
Molecular Weight	477.51 g/mol
Synonyms	1-(Carbazol-4-yloxy)-3-(isopropylamino)-2-propanol Glucuronide; Carazolol β-D-Glucuronide; Carazolol Glucuronide Metabolite; 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-9H-carbazole-9-glucuronide; Carazolol D-Glucuronide; Carazolol Glucuronide Conjugate
EINECS	Contact for details

Quality Control

Our Carazolol Glucuronide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (NMR, IR, MS) and purity assessment by HPLC. A detailed Certificate of Analysis (COA) is provided, documenting the batch-specific results for identity, assay, purity, and related substances. We ensure compliance with relevant standards for high-purity reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccant and inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.