Description

4-Pyridinecarbonylfluoride,2-Fluoro-(9Ci) is a specialized fluorinated pyridine derivative, a high-value building block in advanced organic synthesis. This compound matters for its unique reactivity profile, offering chemists a versatile handle for introducing fluorine and carbonyl functionalities into complex molecular architectures. It is primarily needed by R&D and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalization agent for creating specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the preparation of novel fluorinated ligands for transition metal catalysis and organocatalysis.
• Fluorine Chemistry Research: A valuable reagent for studying nucleophilic aromatic substitution and other fluorination-related reaction mechanisms.
• Diagnostic Agent Synthesis: Potential intermediate in the development of fluorinated contrast agents or radiotracers for medical imaging (e.g., PET).

Basic Information

Product Name	4-Pyridinecarbonylfluoride,2-Fluoro-(9Ci)
CAS No.	116853-95-3
Molecular Formula	C7H3F2NO
Molecular Weight	155.10 g/mol
Synonyms	2-Fluoroisonicotinoyl Fluoride; 2-Fluoro-4-pyridinecarbonyl fluoride; 2-Fluoropyridine-4-carbonyl fluoride; 4-Carbonylfluoride-2-fluoropyridine; Isonicotinoyl fluoride, 2-fluoro-; (2-Fluoropyridin-4-yl)(fluoro)methanone
EINECS	Contact for details

Quality Control

Our 4-Pyridinecarbonylfluoride,2-Fluoro-(9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. While typically supplied at research-grade purity (>95%), specifications can be tailored to meet specific project requirements. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC or NMR), and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Research Grade)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.