Description

4'-Fluoro[1,1'-Biphenyl]-4-Sulfonyl Chloride is a high-purity, specialized organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its reactive sulfonyl chloride group, which serves as a versatile building block for constructing more complex sulfonamide and sulfonate derivatives. This compound is critically needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the biphenyl sulfonyl moiety can confer specific biological activity.
• Material Science Research: Serves as a precursor for creating specialized polymers or functional materials with tailored properties.
• Chemical Biology & Proteomics: Can be utilized as a reactive probe or linker in biochemical research for labeling or modifying biomolecules.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	4'-Fluoro[1,1'-Biphenyl]-4-Sulfonyl Chloride
CAS No.	116748-66-4
Molecular Formula	C12H8ClFO2S
Molecular Weight	270.70 g/mol
Synonyms	4'-Fluorobiphenyl-4-sulfonyl chloride; [1,1'-Biphenyl]-4-sulfonyl chloride, 4'-fluoro-; 4-(4-Fluorophenyl)benzenesulfonyl chloride; p-Fluorobiphenyl-4'-sulfonyl chloride; 4-Fluoro-4'-sulfonylchlorobiphenyl; (4-Fluorophenyl)(4-chlorosulfonylphenyl); 4-Fluorophenyl-4'-sulfonyl Chloride
EINECS	Contact for details

Quality Control

Our 4'-Fluoro[1,1'-Biphenyl]-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.