Description

3,3,3-Trifluoropropanal Dimethylacetal is a high-purity fluorinated acetal building block, essential for introducing the trifluoromethyl group into complex molecular architectures. Its primary value lies in its role as a versatile synthon for the synthesis of trifluoromethyl-substituted pharmaceuticals, agrochemicals, and advanced materials. This compound is particularly critical for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to enhance the metabolic stability and lipophilicity of target molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) containing the trifluoromethyl (CF3) group, a common pharmacophore.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the CF3 group improves biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for fluorinated compounds used in electronic displays and organic light-emitting diodes.
• Fluorinated Polymer Modification: Employed to introduce fluorine into polymer chains, enhancing chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: Acts as a protected aldehyde equivalent in multi-step synthetic routes, particularly useful in Grignard and nucleophilic addition reactions.
• Advanced Material Research: Utilized in R&D for developing new fluorinated surfactants, coatings, and specialty chemicals with unique performance characteristics.

Basic Information

Product Name	3,3,3-Trifluoropropanal Dimethylacetal
CAS No.	116586-94-8
Molecular Formula	C5H9F3O2
Molecular Weight	158.12 g/mol
Synonyms	3,3,3-Trifluoropropionaldehyde dimethyl acetal; 1,1-Dimethoxy-3,3,3-trifluoropropane; 3,3,3-Trifluoropropane-1,1-diol dimethyl ether; (3,3,3-Trifluoropropoxy)methane; Trifluoropropanal dimethyl acetal; 3,3,3-Trifluoropropylidene bis(methyl alcohol); 1,1-Dimethoxy-3,3,3-trifluoropropane
EINECS	Contact for details

Quality Control

Our 3,3,3-Trifluoropropanal Dimethylacetal is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent hydrolysis. Incompatible with strong bases and fluorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.355 - 1.365
Density (g/mL, 20°C)	1.15 - 1.25

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.