Description

1,5-Dichloro-2,4-Bis-Trifluoromethyl-Benzene is a high-value, multi-functional fluorinated aromatic building block. This compound is critical for introducing trifluoromethyl and chloro substituents into complex molecular architectures, significantly altering physical and electronic properties. It is primarily sought after by R&D and production chemists in the pharmaceutical and agrochemical industries for synthesizing advanced active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring lipophilic and electron-withdrawing substituents for enhanced bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the trifluoromethyl group is a critical pharmacophore for activity.
• Liquid Crystal & OLED Materials: Serves as a core building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its ability to modify polarizability and charge transport.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart unique properties such as chemical resistance, thermal stability, and low surface energy.
• Organic Synthesis Reagent: A versatile reagent in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic aromatic substitution for constructing complex, fluorinated aromatic systems.

Basic Information

Product Name	1,5-Dichloro-2,4-Bis-Trifluoromethyl-Benzene
CAS No.	116412-77-2
Molecular Formula	C8H2Cl2F6
Molecular Weight	283.00 g/mol
Synonyms	2,4-Bis(trifluoromethyl)-1,5-dichlorobenzene; 1,5-Dichloro-2,4-bis(trifluoromethyl)benzene; Benzene, 1,5-dichloro-2,4-bis(trifluoromethyl)-; 1,3-Dichloro-2,5-bis(trifluoromethyl)benzene (isomer); α,α,α,α',α',α'-Hexafluoro-3,5-dichloro-p-xylene
EINECS	Contact for details

Quality Control

Our 1,5-Dichloro-2,4-Bis-Trifluoromethyl-Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.