Description

2-(Trifluoromethyl)Nicotinaldehyde is a high-value fluorinated pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the unique reactivity of the aldehyde group and the electron-withdrawing properties of the trifluoromethyl substituent, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the trifluoromethyl group for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated organic semiconductors and liquid crystal materials.
• Chemical Biology Probes: Utilized to create fluorinated analogs for studying metabolic pathways and protein-ligand interactions.

Basic Information

Product Name	2-(Trifluoromethyl)Nicotinaldehyde
CAS No.	116308-35-1
Molecular Formula	C7H4F3NO
Molecular Weight	175.11 g/mol
Synonyms	2-(Trifluoromethyl)pyridine-3-carboxaldehyde; 3-Formyl-2-(trifluoromethyl)pyridine; Nicotinaldehyde, 2-(trifluoromethyl)-; 2-Trifluoromethylnicotinaldehyde; 2-Trifluoromethyl-3-pyridinecarboxaldehyde; Pyridine-3-carboxaldehyde, 2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Nicotinaldehyde is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.