Description

2-Fluoro-4-Phenylpyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining a fluorine atom with a phenyl-substituted pyridine ring, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers and light-emitting components.
• Chemical Biology Probes: Utilized to create fluorinated probes and tags for studying biological mechanisms and protein interactions.
• Custom Synthesis and Scale-up: A starting material for contract research organizations (CROs) and custom synthesis providers for client-specific molecule development.

Basic Information

Product Name	2-Fluoro-4-Phenylpyridine
CAS No.	116241-62-4
Molecular Formula	C11H8FN
Molecular Weight	173.19 g/mol
Synonyms	4-Phenyl-2-fluoropyridine; 2-Fluoro-4-phenylpyridine; 2-Fluoro-4-phenyl-pyridine; Pyridine, 2-fluoro-4-phenyl-; 4-Phenyl-2-fluoro-pyridine; 2-Fluoro-4-phenylpyridine (9CI); 116241-62-4 (CAS RN)
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Phenylpyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.