Description

Antimycin A1B is a specific, high-purity congener of the Antimycin A complex, a potent and well-characterized inhibitor of mitochondrial electron transport. This compound is critical for researchers and manufacturers requiring precise biological activity and consistent performance in biochemical and pharmaceutical applications. It is primarily utilized in life science research, as a reference standard, and in the development of targeted therapeutic agents.

Application

• Biochemical Research: As a specific inhibitor of mitochondrial complex III (bc1 complex) for studying cellular respiration, apoptosis, and energy metabolism.
• Pharmaceutical Reference Standard: Used in quality control and analytical method development for pharmaceutical products containing antimycin derivatives.
• Antifungal Agent Research: Investigation of its potent antifungal properties for potential agricultural or clinical applications.
• Apoptosis Inducer: Utilized in cancer research to study mitochondrial pathways of programmed cell death.
• Insecticide and Piscicide Studies: Exploration of its historical and potential use in pest and fish population management.
• Metabolic Pathway Analysis: A key tool for probing oxidative phosphorylation and ATP synthesis in various biological models.

Basic Information

Product Name	Antimycin A1B
CAS No.	116095-18-2
Molecular Formula	C28H40N2O9
Molecular Weight	548.63 g/mol
Synonyms	Antimycin A1b; Antimycin A 1b; 3-Formamido-2-hydroxybenzoyl-L-threonyl-D-alloisoleucyl-L-valyl-L-methylthreonyl-L-methylthreoninate; 3-Formamidosalicyloyl-L-threonyl-D-alloisoleucyl-L-valyl-L-methylthreonyl-L-methylthreoninate; Antibiotic A1b; NSC 131491
EINECS	Contact for details

Quality Control

Our Antimycin A1B is manufactured under strict quality management systems to ensure the highest standards of purity and consistency. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere to prevent oxidation. The material is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.