Description

Fluoromethyl p-Tolyl Sulfone is a specialized organosulfur compound featuring a fluoromethyl group and a p-tolyl sulfone moiety. This structure makes it a valuable building block and intermediate in advanced organic synthesis, particularly for introducing fluorinated sulfone functionalities. It is primarily utilized by pharmaceutical and agrochemical research organizations engaged in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially those requiring fluorinated sulfone groups for enhanced biological activity or metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluoromethyl sulfone unit can contribute to improved efficacy and environmental profile.
• Material Science Research: Serves as a precursor for novel polymers or functional materials with specific electronic or surface properties.
• Cross-Coupling Reactions: Acts as an electrophilic coupling partner in palladium-catalyzed or other metal-mediated reactions to construct complex molecular architectures.
• Fluorine Chemistry Studies: Employed as a model compound in academic and industrial research exploring the reactivity and applications of fluorinated sulfones.
• Ligand and Catalyst Development: Potential building block for creating specialized ligands used in asymmetric catalysis or metal complexation.

Basic Information

Product Name	Fluoromethyl p-Tolyl Sulfone
CAS No.	115909-68-7
Molecular Formula	C8H9FO2S
Molecular Weight	188.22 g/mol
Synonyms	1-(Fluoromethyl)sulfonyl-4-methylbenzene; p-Tolyl Fluoromethyl Sulfone; 4-Methylphenyl Fluoromethyl Sulfone; (4-Methylphenyl)(fluoromethyl) Sulfone; Fluoromethyl Tosyl Sulfone; α-Fluoro-p-tolyl Methyl Sulfone; Fluoromethyl 4-Methylphenyl Sulfone; 115909-68-7
EINECS	Contact for details

Quality Control

Our Fluoromethyl p-Tolyl Sulfone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.