Description

1-Deoxycastanospermine is a potent and specific glycosidase inhibitor derived from the castanospermine alkaloid family. This compound is a critical biochemical tool for studying carbohydrate metabolism and processing, particularly in the context of viral replication and lysosomal storage disorders. It is essential for researchers and developers in pharmaceutical R&D, biotechnology, and academic biochemistry laboratories focused on enzyme mechanism studies and therapeutic discovery.

Application

• Biochemical Research: A key tool for inhibiting specific α-glucosidase I enzymes to study N-linked glycan processing in cells.
• Antiviral Studies: Investigated for its potential to disrupt the maturation of viral envelope glycoproteins, impacting viruses like HIV and hepatitis.
• Lysosomal Storage Disorder Models: Used in research to induce and study cellular models of diseases such as Gaucher's disease.
• Glycobiology: Fundamental reagent for exploring the role of glycoprotein trimming in cell signaling, adhesion, and immune response.
• Pharmaceutical Intermediate: Serves as a sophisticated chiral building block or precursor for the synthesis of more complex therapeutic candidates.
• Quality Control Standard: Used as a reference standard in analytical laboratories for method development and validation in related drug discovery pipelines.

Basic Information

Product Name	1-Deoxycastanospermine
CAS No.	115649-93-9
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	1-Deoxycastanospermine; (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyoctahydroindolizine; 6,7,8-Trihydroxyindolizidine; Castanospermine, 1-deoxy-; 1,6,7,8-Tetrahydroxyoctahydroindolizine; Octahydro-1,6,7,8-indolizinetetrol
EINECS	Contact for details

Quality Control

Our 1-Deoxycastanospermine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.