Description

2,4-Dichloro-5-Methylbenzotrifluoride is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both chlorine substituents and a trifluoromethyl group, makes it a key intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a substituted benzotrifluoride scaffold for enhanced metabolic stability and lipophilicity.
• Agrochemical Synthesis: Serves as a key building block for developing modern herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to biological activity and environmental persistence.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and halogen/fluorine functionalities.
• Chemical Research & Development: Employed as a standard reagent in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution reactions to introduce complex substituents.
• Dye and Pigment Intermediate: Functions as a starting material for synthesizing specialized dyes and pigments where halogen and fluorine atoms modify color properties and fastness.

Basic Information

Product Name	2,4-Dichloro-5-Methylbenzotrifluoride
CAS No.	115571-61-4
Molecular Formula	C8H5Cl2F3
Molecular Weight	229.03 g/mol
Synonyms	1,3-Dichloro-4-methyl-2-(trifluoromethyl)benzene; 2,4-Dichloro-α,α,α-trifluoro-5-methyltoluene; 5-Methyl-2,4-dichlorobenzotrifluoride; 2,4-Dichloro-5-methyl-α,α,α-trifluorotoluene; Benzene, 1,3-dichloro-4-methyl-2-(trifluoromethyl)-; 2,4-Dichloro-5-(trifluoromethyl)toluene
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5-Methylbenzotrifluoride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance for your synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.