Description

5-Bromo-2-Ethoxy-1,3-Difluorobenzene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules in research and industrial-scale production. This compound is primarily sought by pharmaceutical, agrochemical, and advanced materials chemists for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorobenzene core with orthogonal functional handles.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the bromo and ethoxy groups facilitate further derivatization.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysis.
• Polymer & Resin Modifier: Incorporated into polymer backbones to impart specific properties like chemical resistance, thermal stability, or altered refractive index.
• Chemical Research & Development: A versatile starting material in academic and industrial R&D for exploring new chemical spaces and reaction methodologies.

Basic Information

Item	Details
Product Name	5-Bromo-2-Ethoxy-1,3-Difluorobenzene
CAS No.	115467-04-4
Molecular Formula	C8H7BrF2O
Molecular Weight	237.04 g/mol
Synonyms	1-Bromo-4-ethoxy-2,6-difluorobenzene; 2,6-Difluoro-4-bromophenetole; 4-Bromo-2,6-difluorophenetole; 5-Bromo-1,3-difluoro-2-ethoxybenzene; 2-Ethoxy-5-bromo-1,3-difluorobenzene; 1,3-Difluoro-5-bromo-2-ethoxybenzene; Benzene, 5-bromo-2-ethoxy-1,3-difluoro-
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Ethoxy-1,3-Difluorobenzene is manufactured under strict quality management protocols. We guarantee high purity and batch-to-batch consistency through comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to meet your precise R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.