Description

1-Chloro-2-(Chlorodifluoromethyl)Benzene is a versatile fluorinated aromatic building block, valued for its unique difluoromethyl chloride moiety which imparts significant reactivity and lipophilicity. This compound is essential for the synthesis of advanced agrochemicals and pharmaceutical intermediates, where its structure enables the introduction of fluorine atoms to modulate biological activity and metabolic stability. It is a critical raw material for research and production chemists in the fine chemical, crop protection, and life science industries seeking to develop novel active ingredients.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, where the difluoromethyl group enhances efficacy and environmental profile.
• Pharmaceutical Building Block: Used in medicinal chemistry for the development of active pharmaceutical ingredients (APIs), particularly in candidates targeting central nervous system and metabolic diseases.
• Liquid Crystal & OLED Material Synthesis: Serves as a fluorinated aromatic component in the production of advanced electronic display materials.
• Polymer & Resin Modification: Employed to introduce fluorine into polymer chains, improving chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: Acts as a versatile reagent for nucleophilic substitution and cross-coupling reactions in complex molecule construction.
• Dye & Pigment Manufacturing: Utilized in the synthesis of specialized fluorinated dyes with enhanced lightfastness and color properties.

Basic Information

Product Name	1-Chloro-2-(Chlorodifluoromethyl)Benzene
CAS No.	115345-92-1
Molecular Formula	C7H4Cl2F2
Molecular Weight	213.01 g/mol
Synonyms	2-Chloro-α,α-difluorobenzyl Chloride; 1-Chloro-2-(chlorodifluoromethyl)benzene; o-Chloro-α,α-difluorobenzyl Chloride; Benzene, 1-chloro-2-(chlorodifluoromethyl)-; (2-Chlorophenyl)difluoromethyl Chloride; 2-Chlorobenzylidene Chloride Difluoride; α,α-Difluoro-2-chlorobenzyl Chloride
EINECS	Contact for details

Quality Control

Our 1-Chloro-2-(Chlorodifluoromethyl)Benzene is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency meet the high standards required for industrial and research applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to minimize moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	≤ 2.0% total
Density (20°C)	~1.45 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.