Description

16,18-Ethano-20-Ethyl-6-Oxoprostaglandin E1 Leucinamide is a chemically modified prostaglandin E1 (PGE1) analogue designed for enhanced stability and targeted biological activity. This compound is significant for its potential role in advanced pharmaceutical research, particularly in the development of novel therapeutics targeting specific cellular pathways. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery, especially for programs focused on vascular biology, inflammation, and cytoprotection.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel drug candidates.
• Biochemical Research: Used as a high-purity reference standard or probe in studies of prostaglandin receptors and signal transduction mechanisms.
• Vascular Biology Studies: Investigated for its potential effects on vasodilation, platelet aggregation, and smooth muscle cell proliferation.
• Inflammation & Immunology Research: Applied in experimental models to study modulatory effects on inflammatory mediators and immune cell function.
• Preclinical Development: Utilized in formulation studies and pharmacokinetic/pharmacodynamic (PK/PD) profiling for new chemical entities.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.

Basic Information

Product Name	16,18-Ethano-20-Ethyl-6-Oxoprostaglandin E1 Leucinamide
CAS No.	115288-30-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	6-Oxo-PGE1 Leucinamide Ethano-Ethyl Derivative; 16,18-Ethano-20-ethyl-6-oxo-PGE1 leucinamide; 20-Ethyl-16,18-ethano-6-oxoprostaglandin E1 leucinamide; PGE1 Leucinamide Analog; Modified Prostaglandin E1 Amide; (5Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3S)-3-hydroxy-4-(3-ethyl-2,5-dioxo-1-pyrrolidinyl)-1-butenyl]-5-oxocyclopentyl]-5-heptenamide; Leucinamide Prostaglandin Derivative
EINECS	Contact for details

Quality Control

Our 16,18-Ethano-20-Ethyl-6-Oxoprostaglandin E1 Leucinamide is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.