Description

Mycalamide A CAS NO 115185-92-7 is a potent, naturally occurring marine-derived compound belonging to the class of complex polyketide macrolides. This compound is of significant interest for its unique biological activity profile, particularly as a powerful inhibitor of eukaryotic protein synthesis. It serves as a critical research tool and a promising lead structure for the development of novel therapeutics, primarily targeting oncology and virology research sectors.

Application

• Biomedical Research: As a potent and selective tool compound for studying protein synthesis inhibition, cellular apoptosis pathways, and signal transduction mechanisms.
• Anticancer Agent Development: Serves as a high-value lead molecule in preclinical oncology research for the discovery of new chemotherapeutic agents.
• Antiviral Research: Investigated for its potential activity against various viruses by interfering with viral replication processes within host cells.
• Mechanistic Studies: Used in molecular and cell biology to elucidate the function of the eukaryotic ribosome and the mechanisms of translational control.
• Chemical Biology: Employed in probe development for target identification and validation within complex biological systems.
• Pharmaceutical Reference Standard: Utilized as a certified reference material (CRM) for analytical method development, validation, and quality control in drug discovery pipelines.

Basic Information

Product Name	Mycalamide A
CAS No.	115185-92-7
Molecular Formula	C₂₈H₄₅NO₈
Molecular Weight	523.66 g/mol
Synonyms	Mycalamide A; (-)-Mycalamide A; 115185-92-7; NSC 637850; (1S,2R,3S,4S,6R,7S,8S,11S,12S,14R,16S,18R)-7,12,14,16-Tetrahydroxy-4,8,11,18-tetramethyl-6-[(1E)-1-methyl-2-oxo-2-[(2S,3S)-3-methyl-2-oxo-5-oxolanyl]ethenyl]-3-(2-methyl-1-oxopropoxy)-15-oxatricyclo[12.3.1.02,11]octadec-13-ene-5,9,17-trione
EINECS	Contact for details

Quality Control

Every batch of Mycalamide A is subjected to rigorous analytical characterization to ensure identity, purity, and potency for research applications. Our quality protocols are designed to meet the stringent requirements of pharmaceutical and biotechnology research. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results from HPLC, NMR, and MS analyses to confirm compliance with specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep under an inert atmosphere. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details
Solubility	Soluble in DMSO, methanol; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.