Description

Diaspartyl Chlorin E6 CAS NO 115150-47-5 is a synthetic chlorin derivative, a key photosensitizer in advanced photodynamic therapy (PDT) and photodynamic diagnosis (PDD). Its value lies in its high purity and specific chemical structure, which enables precise light-activated targeting for therapeutic and diagnostic applications. This compound is essential for pharmaceutical R&D, academic research, and the development of next-generation light-based medical treatments.

Application

• Photodynamic Therapy (PDT) Agent: A core photosensitizer for the treatment of various cancers, including skin, esophageal, and lung cancers, activated by specific light wavelengths to destroy malignant cells.
• Photodynamic Diagnosis (PDD): Used in fluorescence-guided surgery and diagnostic imaging to visualize and delineate tumor margins with high precision.
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of more complex, targeted drug conjugates for enhanced therapeutic efficacy.
• Biomedical Research: Employed in academic and industrial laboratories to study mechanisms of photodynamic action, cellular uptake, and new applications in life sciences.
• Dermatology Treatments: Investigated for use in treating actinic keratosis, acne, and other dermatological conditions via light-activated processes.
• Antimicrobial PDT: Explored for its potential in light-activated disinfection and treatment of localized microbial infections.

Basic Information

Item	Detail
Product Name	Diaspartyl Chlorin E6
CAS No.	115150-47-5
Molecular Formula	C50H60N8O12
Molecular Weight	965.06 g/mol
Synonyms	Chlorin e6 Nε,Nε-bis[(2S)-2-aminobutanedioyl]-, (17S,18S)-; Mono-L-aspartyl chlorin e6; NPe6; Talaporfin sodium precursor; LS 11; ASP-002; Photodynamic therapy agent LS11; Laserphyrin intermediate; Chlorin-based photosensitizer
EINECS	Contact for details

Quality Control

Our Diaspartyl Chlorin E6 is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research and development. A Certificate of Analysis (COA) detailing purity, related substances, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. The container should be kept in a cool, dry, and well-ventilated place, away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Dark green to brownish-green powder
Identification (HPLC)	Conforms to reference standard
Identification (UV-Vis)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Single Maximum Unknown Impurity	≤ 1.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.