Description

2,3-Dihydro-1-Benzofuran-5-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in introducing the sulfonyl functional group, enabling the creation of sulfonamides and other valuable intermediates with specific biological or material properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for creating sulfonamide-based therapeutics with potential antimicrobial, anti-inflammatory, or enzyme-inhibitory activity.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the sulfonyl moiety is integral to the compound's mode of action.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, or functional materials with tailored properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling, modifying, or probing biological molecules and proteins in research settings.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	2,3-Dihydro-1-Benzofuran-5-Sulfonyl Chloride
CAS No.	115010-11-2
Molecular Formula	C8H7ClO3S
Molecular Weight	218.66 g/mol
Synonyms	5-Benzofuransulfonyl chloride, 2,3-dihydro-; 2,3-Dihydrobenzofuran-5-sulfonyl chloride; 2,3-Dihydro-1-benzofuran-5-sulfonyl chloride; 1-Benzofuran-5-sulfonyl chloride, 2,3-dihydro-; 2,3-Dihydrobenzo[b]furan-5-sulfonyl chloride; Dihydrobenzofuransulfonyl chloride; 115010-11-2
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1-Benzofuran-5-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically meeting standards suitable for research and development use. Each lot is analyzed using advanced techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.