Description

4-(Fluoromethyl)Benzoylformate is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of a fluoromethyl group can dramatically alter biological activity and metabolic stability. Pharmaceutical R&D teams and fine chemical manufacturers need this high-purity intermediate to create the next generation of fluorinated therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluoromethyl moiety enhances lipophilicity and target binding.
• Liquid Crystal Materials: Serves as a building block for fluorinated components in advanced display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the synthesis of electron-transport or emissive layer materials for high-efficiency devices.
• Advanced Polymer Chemistry: Acts as a monomer or modifier for introducing fluorine into specialty polymers to improve chemical resistance and surface properties.
• Chemical Research & Development: A valuable reagent for exploring new fluorination methodologies and creating compound libraries for screening.

Basic Information

Product Name	4-(Fluoromethyl)Benzoylformate
CAS No.	114996-72-4
Molecular Formula	C10H9FO3
Molecular Weight	196.18 g/mol
Synonyms	4-(Fluoromethyl)benzoylformic acid; α-Oxo-4-(fluoromethyl)benzeneacetic acid; (4-Fluoromethylphenyl)oxoacetic acid; Benzeneacetic acid, α-oxo-4-(fluoromethyl)-; 4-Fluoromethylbenzoylformic acid; p-Fluoromethylbenzoylformate
EINECS	Contact for details

Quality Control

Every batch of 4-(Fluoromethyl)Benzoylformate is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.