Description

Ecteinascidin 770 is a complex marine-derived alkaloid with significant biological activity. This compound is of high interest in pharmaceutical research and development due to its potent cytotoxic properties and unique mechanism of action. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel anticancer agents and other therapeutic candidates.

Application

• Pharmaceutical Research: Serves as a key reference standard and intermediate in the development of novel anticancer therapeutics.
• Biochemical Studies: Used to investigate mechanisms of cytotoxicity, DNA interaction, and topoisomerase inhibition in cellular models.
• Preclinical Development: Acts as a critical starting material or benchmark compound in the synthesis and optimization of new chemical entities (NCEs).
• Academic Research: Employed in university and institutional labs for studying marine natural products and their structure-activity relationships (SAR).
• Process Chemistry: Used in scaling up synthetic routes and developing robust manufacturing processes for related pharmaceutical compounds.

Basic Information

Product Name	Ecteinascidin 770
CAS No.	114899-80-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ecteinascidin-770; ET-770; NSC-684766; 1,2,3,4-Tetrahydro-2-methyl-6,7-methylenedioxy-1-[(3,4,5-trimethoxyphenyl)methyl]isoquinolin-8-ol; Trabectedin analogue; Yondelis analogue
EINECS	Contact for details

Quality Control

Our Ecteinascidin 770 is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. All materials are accompanied by comprehensive analytical data. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store under an inert atmosphere for long-term preservation and to minimize exposure to humidity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.