Description

Chlorin E6 Ethylenediamide is a chemically modified derivative of Chlorin E6, designed for enhanced stability and specific functionalization. This compound is a critical intermediate and active component in advanced photodynamic therapy (PDT) and photodiagnostic applications. It is primarily utilized by pharmaceutical R&D teams, diagnostic reagent manufacturers, and academic research institutions focused on oncology and biomedical imaging.

Application

• Photodynamic Therapy (PDT) Agents: Serves as a key photosensitizer precursor for the development of next-generation cancer treatments.
• Diagnostic Imaging Probes: Used in the synthesis of targeted contrast agents for fluorescence-guided surgery and tumor detection.
• Bioconjugation & Drug Delivery: The ethylenediamide moiety facilitates conjugation to antibodies, peptides, or nanoparticles for targeted therapeutic platforms.
• Academic & Industrial Research: A vital reference standard and building block in photochemistry and medicinal chemistry research.
• Photosensitizer Optimization: Employed to improve the pharmacokinetic properties, such as solubility and tissue selectivity, of chlorin-based compounds.

Basic Information

Product Name	Chlorin E6 Ethylenediamide
CAS No.	114849-41-1
Molecular Formula	C36H40N6O6
Molecular Weight	652.74 g/mol
Synonyms	Chlorin e6 ethylenediamine monoamide; CE6-EDA; 131,151-Bis(2-aminoethyl)amide of Chlorin e6; Pheophorbide a derivative; 3-Devinyl-3-(1-carboxyethyl)pyropheophorbide-a ethylenediamide; Photosensitizer intermediate; Chlorin-based photosensitizer precursor
EINECS	Contact for details

Quality Control

Our Chlorin E6 Ethylenediamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and NMR for structural verification. We provide Certificates of Analysis (COA) with detailed specifications to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at -20°C or below for long-term stability. This product is light-sensitive and easily oxidized; allow it to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Dark green to brown powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.