Description

E6 Berbamine is a high-purity, naturally derived bisbenzylisoquinoline alkaloid, recognized for its significant biological activity and research utility. This compound is of critical importance in pharmaceutical and life science research, particularly in the study of cellular mechanisms and potential therapeutic pathways. It serves as a key reference standard and active pharmaceutical ingredient (API) intermediate for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors.

Application

• Pharmaceutical Research & Development: As a reference standard for quality control and method validation in the analysis of berbamine-containing products and extracts.
• Preclinical Studies: Investigation into its pharmacological properties, including potential anti-cancer, immunomodulatory, and anti-inflammatory activities.
• Active Pharmaceutical Ingredient (API) Intermediate: Used in the synthesis and development of novel drug candidates and formulations.
• Biochemical Research: A tool compound for studying calcium channel blocking activity and its effects on various cell signaling pathways.
• Natural Product Standardization: Employed to standardize herbal extracts and nutraceuticals that contain berbamine or related alkaloids.
• Academic Research: Utilized in university and institutional labs for chemical, biological, and pharmacological research projects.

Basic Information

Product Name	E6 Berbamine
CAS No.	114784-59-7
Molecular Formula	C37H40N2O6
Molecular Weight	608.73 g/mol
Synonyms	Berbamine; (1'β)-2,2'-Dimethyl-6,6',7,12-tetramethoxy-2,2',3'-trimethylenebis(1,2,3,4-tetrahydroisoquinoline); Berbamine (Alkaloid); NSC 146051; BBM; (+)-Berbamine; Berbanum
EINECS	Contact for details

Quality Control

Our E6 Berbamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and MS for identification, and residual solvent analysis, to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.2%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.