Description

2,1,3-Benzoxadiazole-4-Sulfonyl Chloride CAS NO 114322-14-4 is a specialized sulfonyl chloride derivative of benzoxadiazole, serving as a key reactive intermediate in advanced organic synthesis. Its primary value lies in its role as a versatile electrophile for introducing the sulfonamide moiety, enabling the construction of complex molecules with tailored properties. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, especially in the development of sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require the benzoxadiazole-sulfonamide scaffold.
• Material Science Research: Employed in the creation of functional polymers, dyes, and advanced organic electronic materials.
• Bioconjugation & Probe Development: Acts as a reactive handle for labeling biomolecules (proteins, peptides) in biochemical research and diagnostic assay development.
• Chemical Library Synthesis: A valuable reagent for combinatorial and medicinal chemistry in high-throughput screening campaigns.

Basic Information

Product Name	2,1,3-Benzoxadiazole-4-Sulfonyl Chloride
CAS No.	114322-14-4
Molecular Formula	C6H3ClN2O3S
Molecular Weight	218.62 g/mol
Synonyms	4-Chlorosulfonyl-2,1,3-benzoxadiazole; Benzofurazan-4-sulfonyl chloride; 4-(Chlorosulfonyl)-2,1,3-benzoxadiazole; 2,1,3-Benzoxadiazole-4-sulfonyl chloride; 4-BD-sulfonyl chloride; 4-Sulfonyl chloride benzofurazan; 4-Chlorosulfonylbenzofurazan; 4-BD-SO2Cl
EINECS	Contact for details

Quality Control

Our 2,1,3-Benzoxadiazole-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.