Description

5-Hexyn-2-One, 3-Fluoro- (9Ci) is a specialized fluorinated alkyne ketone building block, identified by CAS NO 114156-31-9. This compound is valued for its unique molecular architecture, which combines a reactive terminal alkyne group with a ketone and a fluorine substituent, enabling precise synthetic modifications. It is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom can improve biological activity and environmental persistence.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Utilized in click chemistry and bio-conjugation strategies to label biomolecules or construct molecular probes for diagnostic applications.
• Organic Synthesis Building Block: Provides a versatile platform for further chemical transformations, including Sonogashira couplings, nucleophilic additions, and reduction reactions.

Basic Information

Product Name	5-Hexyn-2-One, 3-Fluoro- (9Ci)
CAS No.	114156-31-9
Molecular Formula	C6H7FO
Molecular Weight	114.12 g/mol
Synonyms	3-Fluoro-5-hexyn-2-one; 1-Fluoro-4-pentyn-3-one; 3-Fluorohex-5-yn-2-one; 5-Hexyn-2-one, 3-fluoro-; 114156-31-9; 3-Fluoro-5-hexyn-2-on; 3-Fluoro-5-hexyn-2-one (9CI)
EINECS	Contact for details

Quality Control

Every batch of 5-Hexyn-2-One, 3-Fluoro- (9Ci) is produced and tested under strict quality management protocols to ensure consistency and purity for research and development purposes. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.