Description

2-Chloro-6-Phenyl-4-(Trifluoromethyl)Nicotinonitrile is a high-value, multi-functional chemical intermediate characterized by its unique trifluoromethyl and nitrile-substituted pyridine core. This compound matters for its role as a critical building block in the synthesis of advanced agrochemicals and pharmaceuticals, where its structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethylpyridine moiety.
• Pharmaceutical Building Block: Used in medicinal chemistry for the research and development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other targeted therapy programs.
• Material Science Research: Serves as a specialty monomer or additive in the development of advanced polymers and functional materials with specific electronic or surface properties.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and coordination chemistry applications.
• Custom Synthesis & Contract Manufacturing: A vital substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Chloro-6-Phenyl-4-(Trifluoromethyl)Nicotinonitrile
CAS No.	114084-91-2
Molecular Formula	C13H6ClF3N2
Molecular Weight	282.65 g/mol
Synonyms	2-Chloro-6-phenyl-4-(trifluoromethyl)nicotinonitrile; 2-Chloro-4-(trifluoromethyl)-6-phenylnicotinonitrile; 2-Chloro-6-phenyl-4-(trifluoromethyl)pyridine-3-carbonitrile; 3-Cyano-2-chloro-6-phenyl-4-(trifluoromethyl)pyridine; 114084-91-2; 2-Chloro-4-trifluoromethyl-6-phenyl-3-cyanopyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Phenyl-4-(Trifluoromethyl)Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.