Description

Prostaglandin A2 Isopropyl Ester is a chemically modified derivative of the naturally occurring prostaglandin A2, designed for enhanced stability and research utility. This compound is a critical synthetic intermediate and a valuable pharmacological tool for studying the biological roles of cyclopentenone prostaglandins, which are involved in cellular stress response and inflammation pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on developing novel therapeutic agents and biochemical probes.

Application

• Pharmaceutical Research & Development: Serves as a key synthetic intermediate in the preparation of novel prostaglandin analogs and drug candidates.
• Biochemical Research: Used as a reference standard and a tool compound to investigate the biological activities of PGA2, including its effects on cell cycle arrest and apoptosis.
• Cell Signaling Studies: Employed in studies exploring the role of cyclopentenone prostaglandins in inflammation, oxidative stress, and heat shock response pathways.
• Fine Chemical Synthesis: Acts as a versatile building block for the synthesis of more complex, biologically active molecules in medicinal chemistry.
• Reference Material: Provides a stable, esterified form of PGA2 for use as a calibrant in analytical methods like HPLC and LC-MS.

Basic Information

Item	Detail
Product Name	Prostaglandin A2 Isopropyl Ester
CAS No.	114084-85-4
Molecular Formula	C23H36O5
Molecular Weight	392.53 g/mol
Synonyms	PGA2 Isopropyl Ester; 9-Oxo-15(S)-hydroxy-prosta-10,13-dien-1-oic Acid Isopropyl Ester; Isopropyl (5Z,13E)-(9S,15S)-9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oate; 15(S)-Hydroxy-9-oxoprosta-10,13-dien-1-oic Acid Isopropyl Ester; Prostaglandin A2 IPA Ester
EINECS	Contact for details

Quality Control

Our Prostaglandin A2 Isopropyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (by HPLC normalization)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.