Description

3-(Ethoxycarbonyl)-2-Fluoropyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. This compound is prized for its unique reactivity profile, enabling the efficient introduction of both fluorine and an ester functional group into complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for creating fluorinated analogs with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, including kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides and herbicides, where the fluorine atom improves lipophilicity and target binding.
• Material Science Precursor: Serves as a monomer or functionalization agent for creating specialty polymers and liquid crystals with tailored electronic properties.
• Chemical Research & Development: A versatile reagent for exploring novel fluorination reactions and constructing complex heterocyclic systems in academic and industrial R&D settings.
• Ligand Synthesis: Employed in the preparation of fluorinated ligands for catalysis, enhancing the performance of metal complexes in asymmetric synthesis.

Basic Information

Product Name	3-(Ethoxycarbonyl)-2-Fluoropyridine
CAS No.	113898-56-9
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	2-Fluoro-3-pyridinecarboxylic acid ethyl ester; Ethyl 2-fluoro-3-pyridinecarboxylate; Ethyl 2-fluoronicotinate; 2-Fluoro-3-(ethoxycarbonyl)pyridine; 3-Carbethoxy-2-fluoropyridine; 2-Fluoropyridine-3-carboxylic acid ethyl ester; 113898-56-9
EINECS	Contact for details

Quality Control

Our 3-(Ethoxycarbonyl)-2-Fluoropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring consistency and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.