Description

Carbobenzoxyphenylalanylarginyldiazomethane is a specialized, protected peptide derivative and a diazomethane-based chemical reagent. This compound is of significant value in advanced organic synthesis and peptide chemistry, serving as a key building block for constructing complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and biochemical tools.

Application

• Peptide Synthesis: Acts as a crucial intermediate for the controlled introduction of specific amino acid sequences in solid-phase and solution-phase peptide synthesis.
• Bioconjugation: Used as a linker or cross-linking agent for attaching peptides to other biomolecules, surfaces, or carrier proteins in bioconjugate development.
• Protease Inhibitor Research: Serves as a precursor or model compound in the design and study of potent and selective protease inhibitors, particularly for arginine-specific enzymes.
• Chemical Biology Probes: Employed in the synthesis of activity-based probes (ABPs) for labeling and studying enzyme activity within complex biological systems.
• Pharmaceutical Intermediate: Functions as a high-value synthetic intermediate in the research and development stages of new drug candidates.
• Academic Research: Utilized in university and institutional laboratories for fundamental studies in organic reaction mechanisms and peptide mimetics.

Basic Information

Item	Detail
Product Name	Carbobenzoxyphenylalanylarginyldiazomethane
CAS No.	113823-66-8
Molecular Formula	C27H34N8O5
Molecular Weight	550.61 g/mol
Synonyms	Z-Phe-Arg-CHN2; Cbz-Phe-Arg-CHN2; Carbobenzoxy-Phe-Arg-diazomethane; Z-Phe-Arg-Diazomethane; Benzyloxycarbonyl-Phenylalanyl-Arginyl-Diazomethane; (Benzyloxy)carbonyl-L-phenylalanyl-N5-[(diazomethyl)carbonyl]-L-ornithine; Protease Inhibitor (arginine-specific); Diazomethane, [[(benzyloxy)carbonyl]-L-phenylalanyl]-L-arginyl-
EINECS	Contact for details

Quality Control

Our Carbobenzoxyphenylalanylarginyldiazomethane is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.