Description

3-Fluoropyridine-4-Carbonitrile CAS NO 113770-88-0 is a versatile fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a nitrile group on the pyridine ring, makes it a critical intermediate for introducing specific functionalities into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides, leveraging the fluorine atom to improve metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and catalysts used in cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the development of advanced organic electronic materials, such as components for OLEDs or conductive polymers.
• Fluorinated Liquid Crystal Synthesis: Acts as a key intermediate for producing fluorinated aromatic compounds used in liquid crystal displays (LCDs).
• Chemical Biology Probe Development: Utilized to create fluorinated analogs of bioactive molecules for studying metabolic pathways and protein interactions.

Basic Information

Product Name	3-Fluoropyridine-4-Carbonitrile
CAS No.	113770-88-0
Molecular Formula	C6H3FN2
Molecular Weight	122.10 g/mol
Synonyms	4-Cyano-3-fluoropyridine; 3-Fluoro-4-cyanopyridine; 3-Fluoropyridine-4-carbonitrile; 3-Fluoro-4-pyridinecarbonitrile; 3-Fluoroisonicotinonitrile; 3-Fluoropyridin-4-yl cyanide; 4-Pyridinecarbonitrile, 3-fluoro-
EINECS	Contact for details

Quality Control

Our 3-Fluoropyridine-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.